Invention Grant
- Patent Title: Hetero ring-fused phenyl compounds for inhibiting TNIK and medical uses thereof
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Application No.: US16967825Application Date: 2019-01-31
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Publication No.: US11447469B2Publication Date: 2022-09-20
- Inventor: Sung Youn Chang , Hyuk Lee , Ki Young Kim , Bum Tae Kim , Sung Soo Kim , Seong Hwan Kim , Hwan Jung Lim , Jung Nyoung Heo , Sang Joon Shin , Sang Youn Park
- Applicant: Korea Research Institute of Chemical Technology , Industry-Academic Cooperation Foundation, Yonsei University
- Applicant Address: KR Daejeon; KR Seoul
- Assignee: Korea Research Institute of Chemical Technology,Industry-Academic Cooperation Foundation, Yonsei University
- Current Assignee: Korea Research Institute of Chemical Technology,Industry-Academic Cooperation Foundation, Yonsei University
- Current Assignee Address: KR Daejeon; KR Seoul
- Agency: Harness, Dickey & Pierce, P.L.C.
- Priority: KR10-2018-0015161 20180207
- International Application: PCT/KR2019/001403 WO 20190131
- International Announcement: WO2019/156438 WO 20190815
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D401/12 ; C07D403/14 ; C07D413/12 ; C07D413/14 ; C07D417/14

Abstract:
The present disclosure provides the compound having inhibitory property against TNIK having a specific chemical structure or its pharmaceutically acceptable salt. The present disclosure also provides a composition comprising the compound or its pharmaceutically acceptable salt. The present disclosure also provides a medical use of the compound, its salt or the composition comprising the compound or its pharmaceutically acceptable salt for treating or preventing cancer. The present disclosure also provides a method of treatment or prevention of cancer comprising administering the compound, its salt or the composition comprising the compound or its salt to a subject in need of such treatment or prevention.
Public/Granted literature
- US20210047300A1 HETERO RING-FUSED PHENYL COMPOUNDS FOR INHIBITING TNIK AND MEDICAL USES THEREOF Public/Granted day:2021-02-18
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