Invention Grant
- Patent Title: Serine protease variants and polynucleotides encoding same
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Application No.: US17148790Application Date: 2021-01-14
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Publication No.: US11447763B2Publication Date: 2022-09-20
- Inventor: Keiichi Ayabe , Tomoko Matsui , Aki Tomiki , Yuma Kurakata , Esben P. Friis , Jens E. Nielsen , Roland Alexander Pache
- Applicant: NOVOZYMES A/S
- Applicant Address: DK Bagsvaerd
- Assignee: NOVOZYMES A/S
- Current Assignee: NOVOZYMES A/S
- Current Assignee Address: DK Bagsvaerd
- Agent David Fazzolare
- Priority: EP16180497 20160721,EP16195078 20161021
- Main IPC: C12N9/58
- IPC: C12N9/58 ; C12P7/06
Abstract:
The present invention relates to protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease belonging to family 53 derived from a strain of Meripilus giganteus. The variants according to the invention have in particular increased thermo-stability, e.g., increased residual activity after 30 min at a temperature in the range from 55 to 60° C. and/or increased thermal denaturation temperature, compared to the parent Meripilus giganteus protease. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
Public/Granted literature
- US20210139876A1 SERINE PROTEASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME Public/Granted day:2021-05-13
Information query
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