- Patent Title: Method for producing somatic cell, somatic cell, and composition
-
Application No.: US16336985Application Date: 2017-09-27
-
Publication No.: US11459546B2Publication Date: 2022-10-04
- Inventor: Yuta Murakami , Yasuhiro Yoshioka , Ping Dai , Toshikazu Yoshikawa , Yoshinori Harada
- Applicant: Kyoto Prefectural Public University Corporation , KATAOKA CORPORATION
- Applicant Address: JP Kyoto; JP Kyoto
- Assignee: Kyoto Prefectural Public University Corporation,KATAOKA CORPORATION
- Current Assignee: Kyoto Prefectural Public University Corporation,KATAOKA CORPORATION
- Current Assignee Address: JP Kyoto; JP Kyoto
- Priority: JPJP2016-193444 20160930,JPJP2016-193445 20160930,JPJP2016-193446 20160930,JPJP2016-193447 20160930,JPJP2016-193448 20160930,JPJP2017-018779 20170203
- International Application: PCT/JP2017/034955 WO 20170927
- International Announcement: WO2018/062269 WO 20180405
- Main IPC: C12N5/077
- IPC: C12N5/077 ; C12N5/0793

Abstract:
The present invention addresses the problem of providing: a method for producing brown adipocytes, osteoblasts, cartilage cells, neural cells, or cardiac cells from somatic cells without performing artificial gene transfer; brown adipocytes, osteoblasts, cartilage cells, neural cells, or cardiac cells; or a composition including a combination of chemical substances that can be used for the aforementioned production method. An example of the present invention is a method for producing brown adipocytes, osteoblasts, cartilage cells, neural cells, or cardiac cells including a step for culturing somatic cells in the presence or absence of an inhibitor or activator selected from the group consisting of an ALK5 inhibitor, an ALK6 inhibitor, an AMPK inhibitor, a cAMP activator, an ALK2 inhibitor, an ALK3 inhibitor, a GSK3 inhibitor, and an Erk inhibitor.
Public/Granted literature
- US20190218516A1 METHOD FOR PRODUCING SOMATIC CELL, SOMATIC CELL, AND COMPOSITION Public/Granted day:2019-07-18
Information query