- 专利标题： Method of measuring accuracy of concentration in sending liquid in gradient and liquid chromatograph having function of executing method
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申请号： US15734639申请日： 2018-12-19
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公开(公告)号： US11486863B2公开(公告)日： 2022-11-01
- 发明人: Satoru Watanabe
- 申请人： SHIMADZU CORPORATION
- 申请人地址： JP Kyoto
- 专利权人： SHIMADZU CORPORATION
- 当前专利权人： SHIMADZU CORPORATION
- 当前专利权人地址： JP Kyoto
- 代理机构： Renner, Otto, Boisselle & Sklar, LLP
- 优先权： JPJP2018-109120 20180607
- 国际申请： PCT/JP2018/046695 WO 20181219
- 国际公布： WO2019/234955 WO 20191212
- 主分类号： G01N30/34
- IPC分类号： G01N30/34 ; G01N30/86 ; G01N30/02
摘要：
An organic solvent containing liquid that does not include a component to be detected by a detector is used as a first solvent, and an organic solvent containing liquid that includes the component to be detected and is adjusted to have a concentration of an organic solvent that prevents a separation column from actually holding the component to be detected is used a second solvent. Further, a mobile phase is sent while a setting value of a concentration of the second solvent in the mobile phase is changed over time with the separation column provided on an analysis flow path, and an actual concentration of the second solvent in the mobile phase is found based on a detection signal of the detector when the mobile phase is sent at each setting value.
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