Invention Grant
- Patent Title: Cytotoxic antibody
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Application No.: US16545736Application Date: 2019-08-20
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Publication No.: US11512292B2Publication Date: 2022-11-29
- Inventor: Boon Hwa Andre Choo , Jiyun Zheng
- Applicant: Agency for Science, Technology and Research
- Applicant Address: SG Singapore
- Assignee: Agency for Science, Technology and Research
- Current Assignee: Agency for Science, Technology and Research
- Current Assignee Address: SG Singapore
- Agency: Choate, Hall & Stewart LLP
- Agent Charles E. Lyon; Brian E. Reese
- Priority: SG201308964-4 20131203
- Main IPC: C07K16/18
- IPC: C07K16/18 ; C12N5/16 ; C07K16/44 ; C12N5/00
Abstract:
An antibody that binds a glycosylated protein is disclosed, wherein the glycosylation comprises the glycan motif Fucα1-2Galβ1-3GlcNAcβ1-3Galβ1 or Fucα1-2Galβ1-3GlcNAc. Antibodies that are cytotoxic against undifferentiated pluripotent cells are also disclosed.
Information query
