Invention Grant
- Patent Title: Compounds useful as inhibitors of helios protein
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Application No.: US16950978Application Date: 2020-11-18
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Publication No.: US11548870B2Publication Date: 2023-01-10
- Inventor: Andrew P. Degnan , Godwin Kwame Kumi , Audris Huang , James Aaron Balog , Ashok Vinayak Purandare , Weifang Shan , Guo Li
- Applicant: Bristol-Myers Squibb Company
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Gary Greenblatt
- Main IPC: C07D407/14
- IPC: C07D407/14 ; C07D401/14 ; C07D413/14 ; C07D417/14 ; C07D487/04 ; C07D491/107 ; A61K31/4439 ; A61P35/00 ; C07D405/14 ; C07D498/18

Abstract:
Disclosed are compounds of Formula (I): or a salt thereof, wherein: Z is CR6R6 or C═O; Ring A is: and R1, R2, R3, R4, R5, m, and n are defined herein. Also disclosed are methods of using such compounds to inhibit Helios protein, and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.
Public/Granted literature
- US20210147383A1 COMPOUNDS USEFUL AS INHIBITORS OF HELIOS PROTEIN Public/Granted day:2021-05-20
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