- 专利标题： Systems, methods and products for minimizing tissue reactions and tissue injury at an infusion site
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申请号： US17083989申请日： 2020-10-29
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公开(公告)号： US11554160B2公开(公告)日： 2023-01-17
- 发明人: Ulrike W. Klueh , Donald L. Kreutzer
- 申请人： Cell and Molecular Tissue Engineering, LLC
- 申请人地址： US CT Avon
- 专利权人： Cell and Molecular Tissue Engineering, LLC
- 当前专利权人： Cell and Molecular Tissue Engineering, LLC
- 当前专利权人地址： US CT Avon
- 代理机构： Alix, Yale & Ristas, LLP
- 主分类号： A61K38/28
- IPC分类号： A61K38/28 ; A61K9/00 ; A61K47/40 ; A61M5/158 ; C07K14/62 ; A61P3/10 ; A61P29/00
摘要：
Products, systems and methods are disclosed for lowering the concentrations of at least one of preservatives and fibrils in a liquid insulin composition. One method comprises replacing at least a portion of at least one of phenol and m-cresol with at least one of cyclodextrins, cyclodextrin polymers, cyclodextrin beads, and an ion exchange resin.
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