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1.发明公开公开(公告)号：US20230270827A1
公开(公告)日：2023-08-31
申请号：US18145471
申请日：2022-12-22
CPC分类号： A61K38/28 , A61K9/0019 , A61K47/40 , A61M5/1582 , A61P3/10 , A61P29/00 , C07K14/62
摘要： Products, systems and methods are disclosed for lowering the concentrations of at least one of preservatives and fibrils in a liquid insulin composition. One method comprises replacing at least a portion of at least one of phenol and m-cresol with at least one of cyclodextrins, cyclodextrin polymers, cyclodextrin beads, and an ion exchange resin.
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2.发明申请Sensors, Cannulas, Collars and Coated Surgical Mesh, and Corresponding Systems and Methods 有权传感器，插管，衣领和涂层外科手术网，以及相应的系统和方法公开(公告)号：US20150257865A1
公开(公告)日：2015-09-17
申请号：US14485313
申请日：2014-09-12
CPC分类号： A61F2/0063 , A61B5/14503 , A61B5/14532 , A61B5/686 , Y10T29/49888
摘要： Disclosed herein are medical products with a layer of dehydrated modified basement membrane preparation formed thereon. The basement membrane has been modified before dehydration of remove low molecular weight components. Methods of making and using the products also are disclosed.
摘要翻译： 本文公开了具有在其上形成的脱水改性基底膜制剂层的医疗产品。 在脱水除去低分子量组分之前，基底膜已被修饰。 制造和使用产品的方法也被公开。
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3.发明授权公开(公告)号：US11554160B2
公开(公告)日：2023-01-17
申请号：US17083989
申请日：2020-10-29
摘要： Products, systems and methods are disclosed for lowering the concentrations of at least one of preservatives and fibrils in a liquid insulin composition. One method comprises replacing at least a portion of at least one of phenol and m-cresol with at least one of cyclodextrins, cyclodextrin polymers, cyclodextrin beads, and an ion exchange resin.
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4.发明授权公开(公告)号：US10821156B2
公开(公告)日：2020-11-03
申请号：US16092566
申请日：2017-04-12
摘要： Products, systems and methods are disclosed for lowering the concentrations of at least one of preservatives and fibrils in a liquid insulin composition. One method comprises replacing at least a portion of at least one of phenol and m-cresol with at least one of cyclodextrins, cyclodextrin polymers, cyclodextrin beads, and an ion exchange resin.
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公开(公告)号：US10405961B2
公开(公告)日：2019-09-10
申请号：US15255484
申请日：2016-09-02
摘要： Disclosed herein are medical products, including a surgical mesh, with a layer of dehydrated modified basement membrane preparation formed thereon. The basement membrane has been modified before dehydration of remove low molecular weight components. In some embodiments, the basement membrane is crosslinked. Methods of making and using the products also are disclosed.
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6.发明授权公开(公告)号：US12109252B2
公开(公告)日：2024-10-08
申请号：US18145471
申请日：2022-12-22
发明人： Ulrike W. Klueh , Donald L Kreutzer
IPC分类号： A61K38/28 , A61K9/00 , A61K31/12 , A61K31/55 , A61K47/40 , A61M5/158 , A61P3/10 , A61P29/00 , C07K14/62
CPC分类号： A61K38/28 , A61K9/0019 , A61K47/40 , A61M5/1582 , A61P3/10 , A61P29/00 , C07K14/62
摘要： Products, systems and methods are disclosed for lowering the concentrations of at least one of preservatives and fibrils in a liquid insulin composition. One method comprises replacing at least a portion of at least one of phenol and m-cresol with at least one of cyclodextrins, cyclodextrin polymers, cyclodextrin beads, and an ion exchange resin.
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公开(公告)号：US20200069409A1
公开(公告)日：2020-03-05
申请号：US16548070
申请日：2019-08-22
摘要： Disclosed herein are medical products, including an implantable device coated with a crosslinked extracellular matrix comprising at least one of Type IV collagen and laminin, wherein the crosslinked extracellular matrix contains no more than 0.024 mg/ml total concentration of glucose, amino acids and salts having a molecular weight of 2000 daltons or less. Corresponding systems and method also are disclosed.
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公开(公告)号：US10130288B2
公开(公告)日：2018-11-20
申请号：US15290139
申请日：2016-10-11
IPC分类号： A61B5/0215 , A61B5/145 , A61L31/14 , A61L31/08 , A61K38/18 , A61B5/1495
摘要： Disclosed herein are sensors with a layer of dehydrated modified basement membrane preparation formed thereon. The basement membrane has been modified before dehydration of remove low molecular weight components. In some embodiments, the basement membrane is crosslinked. Methods of making and using the products also are disclosed.
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公开(公告)号：US20240299149A1
公开(公告)日：2024-09-12
申请号：US17951483
申请日：2022-09-23
CPC分类号： A61F2/0063 , A61L31/10 , A61L31/16 , A61M5/158 , A61B5/14532 , A61B5/686 , A61B2562/18 , A61F2240/001 , A61F2250/0067 , A61L2300/414 , A61L2300/64 , A61M2005/1581 , A61M2205/0205
摘要： Disclosed herein are medical products, including an implantable device coated with an extracellular matrix comprising Type IV collagen and laminin, wherein the implantable device comprises at least one member selected from the group consisting of sensors, meshes and cannulas, and the extracellular matrix contains no more than 0.024 mg/ml total concentration of glucose, amino acids and salts having a molecular weight of 2000 daltons or less. Corresponding systems and method also are disclosed.
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公开(公告)号：US20140275905A1
公开(公告)日：2014-09-18
申请号：US13828854
申请日：2013-03-14
CPC分类号： A61F2/0063 , A61B5/14532 , A61B5/686 , A61B2562/18 , A61F2240/001 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/414 , A61M5/158 , A61M2005/1581 , A61M2205/0205 , C08L89/00
摘要： Disclosed herein is a surgical mesh with a layer of dehydrated basement membrane formed thereon. Methods of making and using the mesh also are disclosed.
摘要翻译： 本文公开了一种手术网，其上形成有脱水基底膜层。 公开了制造和使用网格的方法。
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