Invention Grant
- Patent Title: Method of eliciting a CD8+ cytotoxic response in hepatocellular carcinoma patients with a population of activated T cells
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Application No.: US17728756Application Date: 2022-04-25
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Publication No.: US11559573B2Publication Date: 2023-01-24
- Inventor: Toni Weinschenk , Andrea Mahr , Jens Fritsche , Phillip Mueller , Anita Wiebe , Sarah Kutscher
- Applicant: Immatics Biotechnologies GmbH
- Applicant Address: DE Tuebingen
- Assignee: Immatics Biotechnologies GmbH
- Current Assignee: Immatics Biotechnologies GmbH
- Current Assignee Address: DE Tuebingen
- Agency: McBee Moore & Vanik IP, LLC
- Priority: GB1423016 20141223,GB1501017 20150121
- Main IPC: A61K35/17
- IPC: A61K35/17 ; A61K39/00 ; A61K38/04 ; C07K7/00 ; C07K7/06 ; C07K7/08 ; C07K14/435 ; C07K14/725 ; C07K14/74 ; C07K16/18 ; C12N5/0783 ; C12N15/115 ; G01N33/68 ; A61K51/10 ; A61K35/12

Abstract:
A method of eliciting an immune response in a patient who has a cancer includes administering to said patient a composition containing a population of activated T cells that selectively recognize the cancer cells in the patient that aberrantly express a peptide consisting of the amino acid sequence of GVYDGEEHSV (SEQ ID NO: 303), in which the peptide is in a complex with an MHC molecule.
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