Invention Grant
- Patent Title: Engineered proteins
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Application No.: US17533997Application Date: 2021-11-23
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Publication No.: US11560555B2Publication Date: 2023-01-24
- Inventor: Benjamin Oakes , Sean Higgins , Hannah Spinner , Sarah Denny , Brett T. Staahl , Kian Taylor , Katherine Baney , Isabel Colin , Maroof Adil
- Applicant: Scribe Therapeutics Inc.
- Applicant Address: US CA Alameda
- Assignee: Scribe Therapeutics Inc.
- Current Assignee: Scribe Therapeutics Inc.
- Current Assignee Address: US CA Alameda
- Agency: Cooley LLP
- Main IPC: C12N9/22
- IPC: C12N9/22 ; C12N15/11 ; C12N15/86 ; C12N15/90

Abstract:
Provided herein are engineered proteins comprising a RuvC DNA cleavage domain comprising one or more amino acid modifications, and one or more improved characteristics, relative to a naturally occurring RuvC domain. Also provided are gene editing systems comprising engineered proteins, and methods for use thereof.
Public/Granted literature
- US20220081681A1 ENGINEERED PROTEINS Public/Granted day:2022-03-17
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