- 专利标题: Therapy for transthyretin-associated amyloidosis
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申请号: US17005893申请日: 2020-08-28
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公开(公告)号: US11564899B2公开(公告)日: 2023-01-31
- 发明人: Marc Centellas Casado , Raúl Insa Boronat , Nuria Reig Bolaño , Núria Gavaldà Batalla
- 申请人: SOM INNOVATION BIOTECH, S.L.
- 申请人地址: ES Barcelona
- 专利权人: SOM INNOVATION BIOTECH, S.L.
- 当前专利权人: SOM INNOVATION BIOTECH, S.L.
- 当前专利权人地址: ES Barcelona
- 代理机构: King & Spalding
- 优先权: EP11382326 20111024
- 主分类号: A61K31/165
- IPC分类号: A61K31/165 ; A61K9/16 ; A61K31/198 ; A61K45/06 ; A61K31/12 ; A61K31/353 ; A61K31/603 ; A61K31/423 ; A61K31/192
摘要:
It is provided a catechol-O-methyltransferase (COMT) inhibitor for use in the prevention and/or treatment of transthyretin-associated amyloidosis. It is also provided a catechol-O-methyltransferase (COMT) inhibitor for use in the prevention and/or treatment of transthyretin-associated amyloidosis in combination therapy with another COMT inhibitor, a benzoxazole derivative, iododiflunisal, diflunisal, resveratrol, tauroursodeoxycholic acid, doxocycline, or epigallocatechin-3-gallate.
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