- Patent Title: Compositions and methods for an improved antitumor immune response
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Application No.: US16616087Application Date: 2018-05-24
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Publication No.: US11576933B2Publication Date: 2023-02-14
- Inventor: Peggy A. Thompson , Kevin R. Webster
- Applicant: EFFECTOR THERAPEUTICS, INC.
- Applicant Address: US CA San Diego
- Assignee: EFFECTOR THERAPEUTICS, INC.
- Current Assignee: EFFECTOR THERAPEUTICS, INC.
- Current Assignee Address: US CA San Diego
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- International Application: PCT/US2018/034474 WO 20180524
- International Announcement: WO2018/218072 WO 20181129
- Main IPC: A61K35/17
- IPC: A61K35/17 ; A61P35/00 ; A61K31/343 ; A61K31/4355 ; A61K45/06 ; C07D471/12
Abstract:
The present disclosure provides compositions and methods for improving an antitumor response against non-inflamed solid tumors. Methods of this disclosure include use of an eIF4A inhibitor to promote infiltration of antitumor lymphocytes into a non inflamed solid tumor. Methods of treating cancer associated with a non-inflamed solid tumor are also provided.
Public/Granted literature
- US20200147135A1 COMPOSITIONS AND METHODS FOR AN IMPROVED ANTITUMOR IMMUNE RESPONSE Public/Granted day:2020-05-14
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