- 专利标题: Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers
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申请号: US17516304申请日: 2021-11-01
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公开(公告)号: US11576956B2公开(公告)日: 2023-02-14
- 发明人: Toni Weinschenk , Andrea Mahr , Jens Fritsche , Phillip Mueller , Anita Wiebe , Sarah Kutscher
- 申请人: Immatics Biotechnologies GmbH
- 申请人地址: DE Tuebingen
- 专利权人: Immatics Biotechnologies GmbH
- 当前专利权人: Immatics Biotechnologies GmbH
- 当前专利权人地址: DE Tuebingen
- 代理机构: McBee Moore & Vanik IP, LLC
- 优先权: GB1423016 20141223,GB1501017 20150121
- 主分类号: A61K35/17
- IPC分类号: A61K35/17 ; A61K39/00 ; A61K38/04 ; C07K7/00 ; C07K7/06 ; C07K7/08 ; C07K14/435 ; C07K14/725 ; C07K14/74 ; C07K16/18 ; C12N5/0783 ; C12N15/115 ; G01N33/68 ; A61K51/10 ; A61K35/12
摘要:
A method of eliciting an immune response in a patient who has a cancer includes administering to said patient a composition containing a population of activated T cells that selectively recognize the cancer cells in the patient that aberrantly express a peptide consisting of the amino acid sequence of GVYDGEEHSV (SEQ ID NO: 303), in which the peptide is in a complex with an MHC molecule.
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