A head-holder support for attaching a medical head-holder to a patient table is provided that has a rigid base body, an adjustable and lockable head-holder interface at the base body, which is adapted to adjustably couple the head-holder to the base body by providing at least three degrees of freedom for the spatial relative position between the head-holder and the base body, wherein the at least three degrees of freedom are lockable so as to establish a rigid coupling between the head-holder and the base body, and at least one robotic arm interface at the base body, which is adapted to provide a rigid coupling between a robotic arm and the base body.