- 专利标题： MEK inhibitors and methods of their use
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申请号： US16853043申请日： 2020-04-20
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公开(公告)号： US11597699B2公开(公告)日： 2023-03-07
- 发明人: Naing Aay , Neel Kumar Anand , Charles M. Blazey , Owen Joseph Bowles , Joerg Bussenius , Simona Costanzo , Jeffry Kimo Curtis , Steven Charles DeFina , Larisa Dubenko , Anagha Abhijit Joshi , Abigail R. Kennedy , Angie Inyoung Kim , Elena S. Koltun , Jean-Claire Limun Manalo , Csaba J. Peto , Kenneth D. Rice , Tsze H. Tsang
- 申请人： Exelixis, Inc.
- 申请人地址： US CA Alameda
- 专利权人： Exelixis, Inc.
- 当前专利权人： Exelixis, Inc.
- 当前专利权人地址： US CA Alameda
- 代理机构： Honigman LLP
- 代理商 Heidi M. Berven; Andrew S. Chipouras
- 主分类号： C07D205/04
- IPC分类号： C07D205/04 ; C07D205/06 ; C07D401/06 ; C07D401/12 ; C07D401/14 ; C07D403/04 ; C07D403/06 ; C07D403/12 ; C07D405/12 ; C07D409/06 ; C07D413/12 ; C07D413/14 ; C07D417/12 ; C07D471/04 ; C07D401/04 ; C07D409/12
摘要：
Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.
公开/授权文献
- US20200283383A1 MEK Inhibitors and Methods of Their Use 公开/授权日：2020-09-10
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