Systems and methods for calibrating a Raman amplifier in a photonic line system of an optical network are provided. A method, according to one implementation, includes the step of setting the gain of a plurality of pump lasers of a Raman amplifier to a safe level. For example, the pump lasers are configured to operate at different wavelengths. Also, the Raman amplifier is connected to a fiber span having a specific fiber-type. The safe can be defined as a level that keeps adverse intermodulation effects below a predetermined threshold regardless of the specific fiber-type. In addition, the method includes the step of increasing the gain of the pump lasers without prior knowledge of the specific fiber-type of the fiber span while keeping the adverse intermodulation effects below the predetermined threshold.