Invention Grant
- Patent Title: Melanocortin 4 receptor antagonists and uses thereof
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Application No.: US17341877Application Date: 2021-06-08
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Publication No.: US11643412B2Publication Date: 2023-05-09
- Inventor: Christopher Ryan Butler , Michelle Renee Garnsey , Kevin Alexander Ogilvie , Jana Polivkova , Matthew Forrest Sammons , Aaron Christopher Smith , Qingyi Yang
- Applicant: Pfizer Inc.
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Main IPC: C07D471/20
- IPC: C07D471/20 ; C07D519/00 ; A61K31/438 ; A61P1/08 ; A61P3/04 ; A61P19/00 ; A61P21/00 ; A61P29/00

Abstract:
Described herein are compounds of Formula I:
and their pharmaceutically acceptable salts, wherein R1, R2, R3, X1, Y1, Y2, Y3, Y4 and Y5 are defined herein; their use as MC4R antagonists; pharmaceutical compositions containing such compounds and salts; the use of such compounds and salts to treat, for example, cachexia, anorexia, or anorexia nervosa; and intermediates and processes for preparing such compounds and salts.
and their pharmaceutically acceptable salts, wherein R1, R2, R3, X1, Y1, Y2, Y3, Y4 and Y5 are defined herein; their use as MC4R antagonists; pharmaceutical compositions containing such compounds and salts; the use of such compounds and salts to treat, for example, cachexia, anorexia, or anorexia nervosa; and intermediates and processes for preparing such compounds and salts.
Public/Granted literature
- US20230019853A1 MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF Public/Granted day:2023-01-19
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