Invention Grant
- Patent Title: Vesicles comprising a PTEN inhibitor and uses of same
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Application No.: US17042441Application Date: 2019-03-27
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Publication No.: US11648260B2Publication Date: 2023-05-16
- Inventor: Shulamit Levenberg , Shaowei Guo , Daniel Offen , Nisim Perets
- Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED , RAMOT AT TEL-AVIV UNIVERSITY LTD.
- Applicant Address: IL Haifa
- Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITTED,RAMOT AT TEL-AVIV UNIVERSITY LTD.
- Current Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITTED,RAMOT AT TEL-AVIV UNIVERSITY LTD.
- Current Assignee Address: IL Haifa; IL Tel Aviv
- Agency: Raphael Bellum PLLC
- International Application: PCT/IL2019/050355 2019.03.27
- International Announcement: WO2019/186558A 2019.10.03
- Date entered country: 2020-09-28
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; A61K31/713 ; A61K35/28 ; A61K38/51 ; C12N15/113 ; A61K9/50 ; C12N15/11 ; A61K9/127
Abstract:
The present invention provides pharmaceutical compositions comprising membrane vesicles, including extracellular vesicles including those referred to as exosomes, loaded with an exogenous Phosphatase and tensin homolog (PTEN) inhibitor. Methods of treating neurological diseases, disorders or conditions using the extracellular vesicles are provided. Isolated extracellular vesicles loaded with an exogenous Phosphatase and tensin homolog (PTEN) inhibitor are provided as well.
Public/Granted literature
- US20210077520A1 VESICLES COMPRISING A PTEN INHIBITOR AND USES OF SAME Public/Granted day:2021-03-18
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