Invention Grant
- Patent Title: Method for producing intermediate useful for synthesis of SGLT inhibitor
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Application No.: US17266844Application Date: 2019-08-09
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Publication No.: US11661406B2Publication Date: 2023-05-30
- Inventor: Qing Ri Li , Hee Kyoon Yoon
- Applicant: Daewoong Pharmaceutical Co., Ltd.
- Applicant Address: KR Hwaseong-si
- Assignee: DAEWOONG PHARMACEUTICAL CO., LTD.
- Current Assignee: DAEWOONG PHARMACEUTICAL CO., LTD.
- Current Assignee Address: KR Hwaseong-si
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Priority: KR 20180094261 2018.08.13
- International Application: PCT/KR2019/010123 2019.08.09
- International Announcement: WO2020/036382A 2020.02.20
- Date entered country: 2021-02-08
- Main IPC: C07D307/79
- IPC: C07D307/79

Abstract:
A method of preparing an intermediate useful for the synthesis of a diphenylmethane derivative that can be used as an SGLT inhibitor is described. A method of synthesizing a compound of Formula 7 can address problems of existing synthesis processes requiring the synthesis of the Grignard reagent and management of related substances. In addition, the method can minimize the generation of related substances, and thus does not require reprocessing of reaction products, thereby simplifying the process. Accordingly, the production yield of a diphenylmethane derivative can be maximized.
Public/Granted literature
- US20210292291A1 METHOD FOR PRODUCING INTERMEDIATE USEFUL FOR SYNTHESIS OF SGLT INHIBITOR Public/Granted day:2021-09-23
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