The present disclosure belongs to the technical field of automobile chassis suspension system tests, and provides a loading system and test equipment for an automobile chassis simulation road test. The loading system includes an inclination angle regulation assembly, an automobile weight loading assembly, a rotation angle regulation assembly and a vertical load loading assembly, can simulate to apply various loads which a chassis bears in the real road running process of an automobile, and ensures consistency between a simulation test result and a real automobile test field detection result; and the test equipment further includes a suspension assembly, an acceleration torque assembly and a rotary drum assembly, can simultaneously test the fatigue durability of automobile chassis parts such as a wheel, a suspension and the like, is high in consistency between a test result of the test equipment and a test result of a test field, has universality, can mount wheel and suspension systems of various automobile types and test the fatigue durability of the wheel and suspension systems of various automobile types, shortens the development period of a finished automobile, and reduces the development cost.