Invention Grant
- Patent Title: PROTAC antibody conjugates and methods of use
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Application No.: US16194897Application Date: 2018-11-19
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Publication No.: US11666581B2Publication Date: 2023-06-06
- Inventor: Thomas Pillow , Jack Sadowsky , Leanna Staben , Steven Staben , Binqing Wei , Ingrid Wertz , Pragya Adhikari , Nicole Blaquiere , Peter Dragovich , Wayne Fairbrother
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Alston & Bird LLP
- Main IPC: A61K31/551
- IPC: A61K31/551 ; A61K47/54 ; A61K47/68 ; A61K47/65 ; A61P37/06 ; A61P35/00 ; C07K16/28 ; C07K16/32 ; C12N9/00
Abstract:
The subject matter described herein is directed to antibody-PROTAC conjugates (PACs), to pharmaceutical compositions containing them, and to their use in treating diseases and conditions where targeted protein degradation is beneficial.
Public/Granted literature
- US20190175612A1 PROTAC ANTIBODY CONJUGATES AND METHODS OF USE Public/Granted day:2019-06-13
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