A transport refrigeration system (200) comprising: a vehicle (102) having a refrigerated cargo space (119); a refrigeration unit (22) in operative association with the refrigerated cargo space, the refrigeration unit providing conditioned air to the refrigerated cargo space; a first engine (26) configured to power the refrigeration unit; a plurality of first fuel tanks (330) fluidly connected to the first engine, the plurality of first fuel tanks configured to supply fuel to the first engine, wherein each of the plurality of first fuel tanks includes a lock off valve (450) and a pressure sensor (470) configured to detect a pressure level within each of the first fuel tanks; and one or more engine controllers (54) in electronic communication with each pressure sensor and lock off valve, the one or more engine controllers being configured to adjust at least one of the lock off valves in response to a pressure level detected by at least one of the pressure sensors.