Invention Grant
- Patent Title: Enhanced immune cells using dual shRNA and composition including the same
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Application No.: US16958649Application Date: 2019-01-10
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Publication No.: US11679129B2Publication Date: 2023-06-20
- Inventor: Chan Hyuk Kim , Young-Ho Lee , Yujean Lee , HyeongJi Lee , Sang Hoon Lee
- Applicant: CUROCELL INC. , KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Applicant Address: KR Daejeon
- Assignee: CUROCELL, INC.,KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee: CUROCELL, INC.,KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: KR Daejeon; KR Daejeon
- Agency: Perkins Cole LLP
- Priority: KR 20180004238 2018.01.12
- International Application: PCT/IB2019/050194 2019.01.10
- International Announcement: WO2019/138354A 2019.07.18
- Date entered country: 2020-06-26
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K35/17 ; A61P35/00 ; A61K31/7088 ; A61K38/17 ; A61K39/395 ; C07K14/725 ; C07K14/705 ; C07K16/28 ; C07K14/47 ; C12N5/0783 ; A61K39/00
Abstract:
The present disclosure is broadly concerned with the field of cancer immunotherapy. For example, the present invention generally relates to an immune cell comprising a genetically engineered antigen receptor that specifically binds to a target antigen and a genetic disruption agent that reduces or is capable of reducing the expression in the immune cell of a gene that weakens the function of the immune cell.
Public/Granted literature
- US20210060067A1 ENHANCED IMMUNE CELLS USING DUAL SHRNA AND COMPOSITION INCLUDING THE SAME Public/Granted day:2021-03-04
Information query
IPC分类:
