Invention Grant
- Patent Title: Method of eliciting a CD8+ cytotoxic response in hepatocellular carcinoma patients with a population of activated T cells
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Application No.: US17853344Application Date: 2022-06-29
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Publication No.: US11679147B2Publication Date: 2023-06-20
- Inventor: Toni Weinschenk , Andrea Mahr , Jens Fritsche , Phillip Mueller , Anita Wiebe , Sarah Kutscher
- Applicant: Immatics Biotechnologies GmbH
- Applicant Address: DE Tuebingen
- Assignee: IMMATICS BIOTECHNOLOGIES GMBH
- Current Assignee: IMMATICS BIOTECHNOLOGIES GMBH
- Current Assignee Address: DE Tuebingen
- Agency: McBee Moore & Vanik IP, LLC
- Priority: GB 23016 2014.12.23 GB 01017 2015.01.21
- Main IPC: A61K35/17
- IPC: A61K35/17 ; A61K39/00 ; A61K38/04 ; C07K7/00 ; C07K7/06 ; C07K7/08 ; C07K14/435 ; C07K14/725 ; C07K14/74 ; C07K16/18 ; C12N5/0783 ; C12N15/115 ; G01N33/68 ; A61K51/10 ; A61K35/12
Abstract:
A method of eliciting an immune response in a patient who has a cancer includes administering to said patient a composition containing a population of activated T cells that selectively recognize the cancer cells in the patient that aberrantly express a peptide consisting of the amino acid sequence of GVLPGLVGV (SEQ ID NO: 56), in which the peptide is in a complex with an MHC molecule.
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