Invention Grant
- Patent Title: Tag-sequence-attached two-dimensional cDNA library device, and gene expression analysis method and gene expression analysis apparatus each utilizing same
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Application No.: US17323311Application Date: 2021-05-18
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Publication No.: US11680286B2Publication Date: 2023-06-20
- Inventor: Masataka Shirai , Hideki Kambara , Kiyomi Taniguchi , Maiko Tanabe
- Applicant: Hitachi, Ltd.
- Applicant Address: JP Tokyo
- Assignee: Hitachi, Ltd.
- Current Assignee: Hitachi, Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Crowell & Moring LLP
- The original application number of the division: US14418135
- Main IPC: C12Q1/6837
- IPC: C12Q1/6837 ; C12N15/10

Abstract:
The present invention relates to a method, a device, and an apparatus for analyzing the expression of a gene in single cells. Specifically, the present invention relates to: a device for gene expression analysis, characterized by including a support, in which a nucleic acid probe having a test nucleic acid capture sequence and a known sequence, and further containing a cell recognition tag sequence which differs depending on the difference in position on the surface of the support or in the vicinity of the surface thereof, and a common primer sequence having a known sequence is two-dimensionally distributed and immobilized on the surface of the support or in the vicinity of the surface thereof; and a method and an apparatus using the device for gene expression analysis.
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Information query
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