A soundproof structure body includes a first tube structure and a second tube structure connected to the first tube structure and having a cross-sectional area different from the first tube structure, in which a structure body having a cross-sectional area smaller than a cross-sectional area of the first tube structure is installed in the first tube structure, and a transmission loss in a case where the structure body is installed in the first tube structure with respect to a case where the structure body is not installed in the first tube structure is positive at two frequencies adjacent to each other and difficult to generate an air column resonance mode in the first tube structure. This soundproof structure body generates a soundproof effect even at frequencies other than air column resonance of a tube structure such as a duct or a muffler, has a small size, and can obtain a high transmission loss in a wide-band.