- 专利标题： Azalactam compounds as HPK1 inhibitors
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申请号： US17246551申请日： 2021-04-30
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公开(公告)号： US11684616B2公开(公告)日： 2023-06-27
- 发明人: Joyann Barber , Sujin Cho-Schultz , Matthew L. Del Bel , Rebecca Anne Gallego , Mingying He , Mehran Jalaie , Robert Steven Kania , Michele Ann McTigue , Sajiv Krishnan Nair , Anne-Marie Dechert Schmitt , Jamison Bryce Tuttle , Dahui Zhou , Ru Zhou
- 申请人： PFIZER INC.
- 申请人地址： US NY New York
- 专利权人： PFIZER INC.
- 当前专利权人： PFIZER INC.
- 当前专利权人地址： US NY New York
- 代理商 Alexey Kuznetsov; Bryan C. Zielinski
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D519/00 ; A61K31/444 ; A61K45/06
摘要：
This invention relates to compounds of general Formula I
and pharmaceutically acceptable salts thereof, in which R1, R2, R3a, R3b, and R4 are as defined herein, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.
and pharmaceutically acceptable salts thereof, in which R1, R2, R3a, R3b, and R4 are as defined herein, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.
公开/授权文献
- US20220401424A1 Azalactam Compounds as HPK1 Inhibitors 公开/授权日：2022-12-22
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