Invention Grant
- Patent Title: Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids
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Application No.: US17399774Application Date: 2021-08-11
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Publication No.: US11685710B2Publication Date: 2023-06-27
- Inventor: Daniel J. Siegwart , Jason B. Miller
- Applicant: The Board of Regents of the University of Texas System
- Applicant Address: US TX Austin
- Assignee: The Board of Regents of The University of Texas System
- Current Assignee: The Board of Regents of The University of Texas System
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- The original application number of the division: US15597049 2017.05.16
- Main IPC: C07C311/32
- IPC: C07C311/32 ; C12N15/88 ; C07F9/09 ; C07F9/10 ; C12N15/11 ; B82Y5/00 ; C07C229/06 ; A61K47/69 ; A61K47/54 ; A61K48/00 ; C07C309/14 ; C12N15/113
Abstract:
The present disclosure provides one or more amino lipids such as an amino lipids containing a sulfonic acid or sulfonic acid derivative of the formulas:
wherein the variables are as defined herein. These amino lipids may be used in compositions with one or more helper lipids and a nucleic acid therapeutic agent. These compositions may be used to treat a disease or disorder such as cancer, cystic fibrosis, or other genetic diseases.
wherein the variables are as defined herein. These amino lipids may be used in compositions with one or more helper lipids and a nucleic acid therapeutic agent. These compositions may be used to treat a disease or disorder such as cancer, cystic fibrosis, or other genetic diseases.
Public/Granted literature
- US20210395192A1 CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS Public/Granted day:2021-12-23
Information query
