A mobile robot operation method according to an aspect of the present invention includes: a step for receiving a guidance destination input; a step for generating a global path to the received guidance destination; a step for generating a left travel guideline and a right travel guideline on the left side and the right side of the generated global path; and a step for generating a local path within a travelable range between the left travel guideline and the right travel guideline. Accordingly, the robot operation method may generate a safe and optimal guidance path when providing a guidance service.