Invention Grant
- Patent Title: Phosphopeptide-encoding oligonucleotide libraries and methods for detecting phosphorylation-dependent molecular interactions
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Application No.: US16278610Application Date: 2019-02-18
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Publication No.: US11718849B2Publication Date: 2023-08-08
- Inventor: Jesse Rinehart , Karl Barber , Farren Isaacs , Jeffrey R Sampson
- Applicant: Yale University , Agilent Technologies, Inc.
- Applicant Address: US CT New Haven
- Assignee: AGILENT TECHNOLOGIES, INC.
- Current Assignee: AGILENT TECHNOLOGIES, INC.
- Current Assignee Address: US CA Santa Clara
- Agency: Mannava & Kang, P.C.
- Agent Carol L. Bunner
- Main IPC: C12N15/10
- IPC: C12N15/10
Abstract:
The present invention relates to libraries of phosphopeptide-encoding oligonucleotides and methods of preparing such libraries. The present invention also relates to methods of detecting, visualizing, or screening for phosphorylation-dependent protein-protein interactions using recombinant phosphopeptides and/or phosphopeptide-encoding oligonucleotides. The present invention also relates to sets or kits of oligonucleotides having regions that encode phosphopeptides.
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