- 专利标题： Therapeutic oligonucleotides
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申请号： US17166071申请日： 2021-02-03
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公开(公告)号： US11725023B2公开(公告)日： 2023-08-15
- 发明人: Heather O'Neill , Günter Mayer , Mark Miglarese , David Spetzler
- 申请人： Caris Science, Inc.
- 申请人地址： US TX Irving
- 专利权人： Caris Science, Inc.
- 当前专利权人： Caris Science, Inc.
- 当前专利权人地址： US TX Irving
- 代理机构： Fish & Richardson P.C.
- 主分类号： C12N15/115
- IPC分类号： C12N15/115 ; C07H19/173 ; A61K47/69 ; A61P37/00 ; A61P25/28 ; A61P31/00 ; A61P9/00 ; A61P35/02 ; A61P29/00 ; A61K9/00 ; C07H19/09 ; C07H19/19 ; C07H21/00 ; C12N15/10 ; C12Q1/6886 ; G06T7/00 ; G01N33/574 ; G01N33/53 ; G01N33/68
摘要：
Methods and compositions are provided for oligonucleotides that bind targets of interest. The targets include cells and microvesicles, such as those derived from various diseases. The oligonucleotides can be used for diagnostic and therapeutic purposes. The target of the oligonucleotides can be a target such as PARP1, HIST1H1B, HIST1H1D, NCL, FBL, SFPQ, RPL12, ACTB, HIST1H4A, SSBP1, NONO, H2AFJ, and DDX21, or a complex, subunit or fragment thereof.
公开/授权文献
- US20220356203A1 THERAPEUTIC OLIGONUCLEOTIDES 公开/授权日：2022-11-10
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