Invention Grant
- Patent Title: Inhibitors of receptor interacting protein kinase I for the treatment of disease
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Application No.: US17033104Application Date: 2020-09-25
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Publication No.: US11753381B2Publication Date: 2023-09-12
- Inventor: Richard T. Lewis , Matthew Michael Hamilton , William J. Ray , Fernando Alvarez , Dana E. Pfaffinger , Naphtali Reyna , Jason Cross , Suyambu Kesava Vijayan Ramaswamy
- Applicant: Board of Regents, The University of Texas System
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agent Cynthia Hathaway; Lauren L. Stevens; Erik M. Larsen
- Main IPC: C07D231/06
- IPC: C07D231/06 ; A61K31/4965 ; A61K31/415 ; A61K31/416 ; C07D231/56 ; C07D403/12 ; A61K31/506 ; A61K31/5377 ; C07D401/14 ; A61K31/4439 ; C07D471/04 ; A61K31/437 ; C07D403/08 ; A61K31/4155 ; C07D413/08 ; A61K31/4245 ; A61K31/4184 ; C07D207/10 ; A61K31/40 ; A61K31/4015 ; C07D401/12 ; C07D403/14 ; A61K31/497 ; A61K31/4192 ; C07D487/04 ; A61K31/4985 ; C07D417/14 ; A61K31/427 ; C07D241/24 ; A61K45/06
Abstract:
Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.
Public/Granted literature
- US20210094921A1 INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE Public/Granted day:2021-04-01
Information query
