Invention Grant
- Patent Title: Optically controlled virus protein, gene thereof, and virus vector containing said gene
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Application No.: US16629925Application Date: 2018-07-11
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Publication No.: US11753448B2Publication Date: 2023-09-12
- Inventor: Kenzaburo Tani , Moritoshi Sato , Makoto Takeda , Maino Tahara
- Applicant: THE UNIVERSITY OF TOKYO
- Applicant Address: JP Tokyo
- Assignee: THE UNIVERSITY OF TOKYO
- Current Assignee: THE UNIVERSITY OF TOKYO
- Current Assignee Address: JP Tokyo
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Priority: JP 17135579 2017.07.11
- International Application: PCT/JP2018/026211 2018.07.11
- International Announcement: WO2019/013258A 2019.01.17
- Date entered country: 2020-01-09
- Main IPC: C07K14/08
- IPC: C07K14/08 ; C12N5/10 ; C12N15/62 ; C12N7/00 ; C12N15/86 ; C07K14/005 ; C12N15/63 ; C12N5/074
Abstract:
The purpose of the present invention is to develop a virus vector, the activity of which is rendered controllable. A virus protein gene derived from an RNA virus is provided in which a gene encoding an optical switch protein is inserted into a foreign gene introducible region of the virus protein so as to enable expression of the gene. By means of this virus vector, it is possible to control, with irradiation of light, enzyme activity of the virus protein and virus vector activity based thereon.
Public/Granted literature
- US20210087234A1 OPTICALLY CONTROLLED VIRUS PROTEIN, GENE THEREOF, AND VIRUS VECTOR CONTAINING SAID GENE Public/Granted day:2021-03-25
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