Invention Grant
- Patent Title: CTLA-4 variant immunomodulatory proteins and uses thereof
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Application No.: US16755072Application Date: 2018-10-09
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Publication No.: US11753458B2Publication Date: 2023-09-12
- Inventor: Lawrence Evans , Joseph L. Kuijper , Ryan Swanson
- Applicant: Alpine Immune Sciences, Inc.
- Applicant Address: US WA Seattle
- Assignee: Alpine Immune Sciences, Inc.
- Current Assignee: Alpine Immune Sciences, Inc.
- Current Assignee Address: US WA Seattle
- Agency: COOLEY, LLP
- International Application: PCT/US2018/055095 2018.10.09
- International Announcement: WO2019/074983A 2019.04.18
- Date entered country: 2020-04-09
- Main IPC: C07K14/705
- IPC: C07K14/705 ; A61K47/65 ; A61P19/02 ; A61K35/17 ; C07K14/725 ; C12N5/0783 ; C12N15/00
Abstract:
Provided herein are variant CTLA-4 polypeptides and immunomodulatory proteins and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of disease applications, including for treatment of autoimmune or inflammatory conditions. Compositions and methods for making and using such proteins are provided.
Public/Granted literature
- US20200308249A1 CTLA-4 VARIANT IMMUNOMODULATORY PROTEINS AND USES THEREOF Public/Granted day:2020-10-01
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