Invention Grant
- Patent Title: Copper supplementation for control of glycosylation in mammalian cell culture process
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Application No.: US17591171Application Date: 2022-02-02
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Publication No.: US11753668B2Publication Date: 2023-09-12
- Inventor: Fernie Mitchelson , Erik Hughes , Jessica Mondia , Robin Parish Hyde-Deruyscher
- Applicant: Biogen MA Inc.
- Applicant Address: US MA Cambridge
- Assignee: Biogen MA Inc.
- Current Assignee: Biogen MA Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C12P21/00
- IPC: C12P21/00 ; C12N5/00 ; C07K16/28
Abstract:
The present invention pertains to a cell culture medium comprising copper as a media supplement, which was shown to control recombinant protein glycosylation and methods of sing thereof. The present invention further pertains to a method of controlling or manipulating glycosylation of a recombinant protein of interest in a large scale cell culture.
Public/Granted literature
- US20220315973A1 COPPER SUPPLEMENTATION FOR CONTROL OF GLYCOSYLATION IN MAMMALIAN CELL CULTURE PROCESS Public/Granted day:2022-10-06
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