An image capturing assembly is provided and includes a fixture, a lens assembly, an image sensing device and a circuit board. The fixture includes a fixture body and at least one first contact. An accommodating space is formed on the fixture body. The at least one first contact is disposed on the fixture body. The lens assembly is engaged with the fixture body. The image sensing device is disposed inside the accommodating space. The image sensing device includes at least one second contact electrically connected to the at least one first contact. The circuit board includes a board body and at least one third contact. The board body is perpendicular to and affixed with the fixture body. The at least one third contact is disposed on the board body and electrically connected to the at least one first contact. Besides, a related endoscope is further provided.