The present disclosure relates to an active substance carrier comprising a core-shell network structure formed using a biopolymer. In an aspect of the present disclosure, the core-shell network structure comprises a core-shell particle comprising: a core comprising prolamin; and a shell comprising pullulan and pectin, wherein the pullulan comprised in the shell surrounds the core and the pectin is located in the outermost layer of the shell, so that a network is formed between the core-shell particles. It can effectively facilitate the transdermal absorption of an active substance.