公开(公告)号：US20250064707A1

公开(公告)日：2025-02-27

申请号：US18697270

申请日：2022-09-27

Applicant: CAREGEN CO., LTD.

Inventor： Yong Ji CHUNG ,  Eun Mi KIM ,  Eung Ji LEE ,  Hana KANG ,  Bobyeol HWANG

IPC: A61K8/64 ,  A61Q19/08 ,  C07K7/06

Abstract: The present invention relates to a peptide having anti-aging activity and a composition for skin regeneration or suppressing skin aging, comprising the peptide as an active ingredient. The peptide according to the present invention, comprising an amino acid sequence of SEQ ID NO: 1, has anti-aging activity and thus can be used as a raw material for a cosmetic product for skin regeneration or suppressing skin aging or as a raw material for a pharmaceutical product for preventing, ameliorating, or treating photoaging.

公开(公告)号：US20250064700A1

公开(公告)日：2025-02-27

申请号：US18678764

申请日：2024-05-30

Applicant: Curl Cult LLC

Inventor： Janine Jarman ,  Lucca Papetti

IPC: A61K8/46 ,  A45D7/04 ,  A61K8/22 ,  A61K8/39 ,  A61K8/44 ,  A61K8/64 ,  A61Q5/04

Abstract: Compositions, products, systems, kits, and methods of perming hair may include a first-product (perming lotion) that contains cysteamine and cysteine, such that the first-product is used to break preexisting disulfide bonds in hair, and then a second-product may be applied directly over (on top of) the first-product to neutralize the effects of the first-product without first rinsing the hair to remove the first-product, so that disulfide bonds in the hair may form to set the treated hair into a desired shape with desired curls, waves, texture, and/or style. Various on-the-rod, off-the-rod, and/or perm tools may be used to maintain the hair in the desired shape until the first-product and the second-product have finished acting on the hair and/or on each other. The Compositions, products, systems, kits, and methods of perming hair are vegan, cruelty free, paraben free, sulfate surfactant free, use minimal water, and are without thioglycolic acid.

公开(公告)号：US12226519B2

公开(公告)日：2025-02-18

申请号：US17114152

申请日：2020-12-07

Applicant: Stellar Biome Inc.

Inventor： Natalia Yudina ,  Maxim Daniel Seferovic

IPC: A61K8/99 ,  A61K8/64 ,  A61K35/747 ,  A61Q11/00

Abstract: Compositions for use in oral hygiene contain a Lactobacillus helveticus strain. Compositions further containing a Lactobacillus plantarum strain, especially Lactobacillus plantarum SD5870, are particularly effective. The combination of Lactobacillus helveticus LAFTI L10 and Lactobacillus plantarum SD5870 synergistically improves oral hygiene. The compositions are particularly useful against dental caries.

公开(公告)号：US20250054582A1

公开(公告)日：2025-02-13

申请号：US18687338

申请日：2022-08-25

Applicant: THE BOOTS COMPANY PLC

Inventor： Mark Johnson ,  Beverley Jane Elms ,  Paul James Tomlinson

IPC: G16C20/30 ,  A61K8/64 ,  A61Q19/00

Abstract: Computer implemented methods of choosing a solvent for a matrikine, apparatus and computer readable methods for implementing the computer implemented methods, methods of creating a matrikine composition, compositions (e.g., cosmetic compositions) made by the methods, for implementing the methods, and uses thereof are provided.

公开(公告)号：US12220474B2

公开(公告)日：2025-02-11

申请号：US18318647

申请日：2023-05-16

Applicant: Two Lines Inc.

Inventor： Allison Anne Conrad ,  Jason Timothy Small ,  Natalye Hinkson

IPC: A61K8/64 ,  A61K8/9789 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/12

Abstract: Provided herein are formulations and methods for conferring at least one beneficial hair care effect. The formulations a unique combination of non-synthetic extracts, and may also comprise palmitoyl tetrapeptide-20 and conditioning agents. Beneficial hair care effects conferred include amelioration of hair depigmentation, promotion and maintenance of hair pigmentation, and enhanced hair growth and volume.

公开(公告)号：US20250009640A1

公开(公告)日：2025-01-09

申请号：US18489869

申请日：2023-10-19

Applicant: TCI CO., LTD.

Inventor： YUNG-HSIANG LIN ,  PEI-YI WU

IPC: A61K8/9728 ,  A61K8/49 ,  A61K8/64 ,  A61K8/67 ,  A61K31/405 ,  A61K31/455 ,  A61K36/06 ,  A61K38/08 ,  A61P39/06 ,  A61Q5/00 ,  A61Q19/00 ,  A61Q19/08

Abstract: A method for improving skin condition, hair health, anti-inflammation activity, cardiovascular health, anti-oxidation activity, anti-aging activity, and/or relieving body fatigue in a subject in need thereof is provided. The method includes administering to the subject a composition comprising yeast powder having at least 5000 ppm of nicotinamide mononucleotide. The yeast powder is prepared by: preparing a first medium, a second medium and a third medium, wherein components of the first, second, and third media comprise nicotinamide, tryptophan, and niacin; inoculating the first medium with yeast for fermentation to obtain a first fermentation broth; inoculating the second medium with the first fermentation broth for fermentation to obtain a second fermentation broth; inoculating the third medium with the second fermentation broth for fermentation to obtain a third fermentation broth; and centrifuging the third fermentation broth to obtain a fermented product, and drying the fermented product to obtain the yeast powder.

公开(公告)号：US20240424069A1

公开(公告)日：2024-12-26

申请号：US18633691

申请日：2024-04-12

Applicant: Medy-Tox, Inc.

Inventor： Hyun Ho Jung ,  Gi Hyeok Yang ,  Hyun Jee Kim ,  Chang Hoon Rhee

IPC: A61K38/48 ,  A61K8/64 ,  A61K8/66 ,  A61K9/00 ,  A61K9/19 ,  A61Q19/08

Abstract: The invention relates to the use of an animal-protein-free botulinum toxin composition to treat a disease, disorder or condition in a patient in need thereof whereby the animal-protein-free botulinum toxin composition exhibits a longer lasting effect in the patient compared to an animal-protein-containing botulinum toxin composition.

公开(公告)号：US20240424061A1

公开(公告)日：2024-12-26

申请号：US18752711

申请日：2024-06-24

Applicant: Samuel E. Lynch

Inventor： Samuel E. Lynch

IPC: A61K38/18 ,  A61K8/64 ,  A61K9/00 ,  A61K31/137 ,  A61K31/167 ,  A61K47/36 ,  A61K47/42 ,  A61P17/02 ,  A61Q19/00 ,  A61Q19/08

Abstract: Compositions of rhPDGF-BB for skin or soft tissue repair, regeneration, rejuvenation, comfort, reinforcement or aesthetic utility in the domains of cosmetics and cosmeceuticals comprising rhPDGF-BB combined with a carrier selected from the group consisting of differing types of collagen, gelatin, alginates, polysaccharides, glycosaminoglycans, fibrin, hyaluronic acid and derivatives or combinations thereof, wherein skin or soft tissue disruption is treated by applying the disclosed compositions.

公开(公告)号：US12171859B2

公开(公告)日：2024-12-24

申请号：US17824425

申请日：2022-05-25

Applicant: ALLERGAN SALES, LLC

Inventor： Patrick Nido ,  Kuniko Kadoya ,  Prithwiraj Maitra ,  Rahul Mehta ,  Elizabeth Makino

IPC: A61K8/64 ,  A61K8/81 ,  A61K8/89 ,  A61K8/9728 ,  A61K8/9783 ,  A61Q19/06

Abstract: The present invention relates to a topical composition that can be used to treat skin laxity, cellulite and to firm, smooth and/or tone skin.

公开(公告)号：US12171812B2

公开(公告)日：2024-12-24

申请号：US18172787

申请日：2023-02-22

Applicant: GemVax & KAEL Co., Ltd.

Inventor： Sang Jae Kim ,  Kyung Hee Kim ,  Kyu-Yong Lee ,  Seong-Ho Koh ,  Hyun-Hee Park ,  Sung Jin Huh ,  Woo Jin Lee ,  Bum Joon Kim

IPC: A61K38/45 ,  A23L33/18 ,  A61K8/64 ,  A61K38/00 ,  A61Q19/00 ,  C07K7/08 ,  C07K14/47 ,  C12N9/02

Abstract: A peptide with anti-inflammatory activity is described, wherein the peptide comprises at least one amino acid sequence among SEQ ID NO: 2 to SEQ ID NO: 179, the peptide has above 80% homology of amino acid sequence with above-mentioned sequences, or the peptide is the fragment of the above-mentioned peptides. An inflammatory composition comprising the above mentioned peptides is also described. The peptides that have at least one amino acid sequence of SEQ ID NO: 2 to SEQ ID NO: 179 shows outstanding efficacy in both suppressing inflammation and in prophylactic means. Therefore, the composition comprising those peptides can be used as anti-inflammatory pharmaceutical compositions or as cosmetic compositions, in turn, treating and preventing a variety of different types of inflammatory diseases.