Invention Grant
- Patent Title: Isoquinolinyl triazolone complexes
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Application No.: US17145006Application Date: 2021-01-08
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Publication No.: US11786608B2Publication Date: 2023-10-17
- Inventor: Rongliang Chen , Padma Manam , Lu Zeng
- Applicant: Takeda Pharmaceutical Company Limited , Rongliang Chen , Padma Manam , Lu Zeng
- Applicant Address: JP CA Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agent Matthew J. Russo
- Main IPC: A61K47/69
- IPC: A61K47/69 ; C07D401/14 ; A61K31/4725 ; A61K31/519 ; C08B37/16

Abstract:
Disclosed is a complex of a compound of Formula 1,
a stereoisomer thereof, or a tautomer of the compound of Formula 1 or stereoisomer thereof, and a cyclodextrin, in which the complex is an amorphous solid. This disclosure also relates to materials and methods for preparing the complex, to pharmaceutical compositions which contain the complex, and to the use of the complex to treat Type I hypersensitivity reactions, autoimmune diseases, inflammatory disorders, cancer, non-malignant proliferative disorders, and other conditions associated with BTK.
a stereoisomer thereof, or a tautomer of the compound of Formula 1 or stereoisomer thereof, and a cyclodextrin, in which the complex is an amorphous solid. This disclosure also relates to materials and methods for preparing the complex, to pharmaceutical compositions which contain the complex, and to the use of the complex to treat Type I hypersensitivity reactions, autoimmune diseases, inflammatory disorders, cancer, non-malignant proliferative disorders, and other conditions associated with BTK.
Public/Granted literature
- US20210138086A1 ISOQUINOLINYL TRIAZOLONE COMPLEXES Public/Granted day:2021-05-13
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