- 专利标题: Process for preparing nano-or microparticles comprising a carrier-polymer and one or more biologically active ingredients
-
申请号: US17758554申请日: 2020-10-29
-
公开(公告)号: US11819576B2公开(公告)日: 2023-11-21
- 发明人: Michael Damm , Andrea Engel , Melanie Liefke
- 申请人: Evonik Operations GmbH
- 申请人地址: DE Essen
- 专利权人: Evonik Operations GmbH
- 当前专利权人: Evonik Operations GmbH
- 当前专利权人地址: DE Essen
- 代理机构: Grüneberg and Myers PLLC
- 优先权: EP 206467 2019.10.31
- 国际申请: PCT/EP2020/080354 2020.10.29
- 国际公布: WO2021/083989A 2021.05.06
- 进入国家日期: 2022-07-08
- 主分类号: A61K9/16
- IPC分类号: A61K9/16 ; A61K31/41 ; A61K31/536 ; A61K31/635 ; A61K31/045 ; A61K31/4184 ; A61K31/496
摘要:
A process can be used for preparing nano- or microparticles containing a carrier-polymer and a biologically active ingredient. The process is a solvent emulsion process involving an organic phase (OP) and an aqueous phase (AP) to form an emulsion. In the case of an oil-in-water emulsion (O/W), the organic phase (OP) contains the biologically active ingredient dissolved or dispersed therein. Alternatively, in the case of a water-in-oil emulsion (W1/O), the aqueous phase (AP) contains the biologically active ingredient dissolved or dispersed therein. The organic phase (OP) is saturated with the salt-containing aqueous phase (AP) and vice versa.
公开/授权文献
信息查询