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公开(公告)号:US11819576B2
公开(公告)日:2023-11-21
申请号:US17758554
申请日:2020-10-29
发明人: Michael Damm , Andrea Engel , Melanie Liefke
IPC分类号: A61K9/16 , A61K31/41 , A61K31/536 , A61K31/635 , A61K31/045 , A61K31/4184 , A61K31/496
CPC分类号: A61K9/1694 , A61K9/1635 , A61K31/045 , A61K31/41 , A61K31/4184 , A61K31/496 , A61K31/536 , A61K31/635
摘要: A process can be used for preparing nano- or microparticles containing a carrier-polymer and a biologically active ingredient. The process is a solvent emulsion process involving an organic phase (OP) and an aqueous phase (AP) to form an emulsion. In the case of an oil-in-water emulsion (O/W), the organic phase (OP) contains the biologically active ingredient dissolved or dispersed therein. Alternatively, in the case of a water-in-oil emulsion (W1/O), the aqueous phase (AP) contains the biologically active ingredient dissolved or dispersed therein. The organic phase (OP) is saturated with the salt-containing aqueous phase (AP) and vice versa.