- 专利标题： Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof
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申请号： US18160442申请日： 2023-01-27
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公开(公告)号： US11820748B2公开(公告)日： 2023-11-21
- 发明人: Elaine Greer , Stephen Anderson , Mark Maloney , Shu Yu , Ekaterina Albert , Emily Rigsbee
- 申请人： Pfizer Inc.
- 申请人地址： US NY New York
- 专利权人： PFIZER INC.
- 当前专利权人： PFIZER INC.
- 当前专利权人地址： US NY New York
- 代理机构： Blank Rome LLP
- 分案原申请号： US17180296 2021.02.19
- 主分类号： C07D233/88
- IPC分类号： C07D233/88 ; A61K31/40
摘要：
The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.
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