公开(公告)号：US11905255B1

公开(公告)日：2024-02-20

申请号：US18361472

申请日：2023-07-28

申请人： Pfizer Inc.

发明人： Elaine Greer ,  Stephen Anderson ,  Mark Maloney ,  Shu Yu ,  Ekaterina Albert ,  Emily Rigsbee

IPC分类号： C07D233/88 ,  A61K31/40

CPC分类号： C07D233/88 ,  A61K31/40 ,  C07B2200/13

摘要： The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

公开(公告)号：US11884634B2

公开(公告)日：2024-01-30

申请号：US18057633

申请日：2022-11-21

申请人： Pfizer Inc.

发明人： Elaine Greer ,  Stephen Anderson ,  Mark Maloney ,  Shu Yu ,  Ekaterina Albert ,  Emily Rigsbee

IPC分类号： A61K31/40 ,  C07D233/88 ,  A61P21/00

CPC分类号： C07D233/88 ,  A61P21/00 ,  A61K31/40 ,  C07B2200/13

摘要： The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

公开(公告)号：US11845732B2

公开(公告)日：2023-12-19

申请号：US18170884

申请日：2023-02-17

申请人： Pfizer Inc.

发明人： Elaine Greer ,  Stephen Anderson ,  Mark Maloney ,  Shu Yu ,  Ekaterina Albert ,  Emily Rigsbee

IPC分类号： A61K31/40 ,  C07D233/88

CPC分类号： C07D233/88 ,  A61K31/40 ,  C07B2200/13

摘要： The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

公开(公告)号：US11566006B2

公开(公告)日：2023-01-31

申请号：US17180296

申请日：2021-02-19

申请人： Pfizer Inc.

发明人： Elaine Greer ,  Stephen Anderson ,  Mark Maloney ,  Shu Yu ,  Ekaterina Albert ,  Emily Rigsbee

IPC分类号： C07D233/88 ,  A61K31/40

摘要： The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

公开(公告)号：US10710966B1

公开(公告)日：2020-07-14

申请号：US16818863

申请日：2020-03-13

申请人： Pfizer Inc.

发明人： Elaine Greer ,  Stephen Anderson ,  Mark Maloney ,  Shu Yu ,  Ekaterina Albert ,  Emily Rigsbee

IPC分类号： C07D233/88 ,  A61K31/40

摘要： The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

公开(公告)号：US11820748B2

公开(公告)日：2023-11-21

申请号：US18160442

申请日：2023-01-27

申请人： Pfizer Inc.

发明人： Elaine Greer ,  Stephen Anderson ,  Mark Maloney ,  Shu Yu ,  Ekaterina Albert ,  Emily Rigsbee

IPC分类号： C07D233/88 ,  A61K31/40

CPC分类号： C07D233/88 ,  A61K31/40 ,  C07B2200/13

摘要： The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

公开(公告)号：US20210269407A1

公开(公告)日：2021-09-02

申请号：US17180296

申请日：2021-02-19

申请人： Pfizer Inc.

发明人： Elaine GREER ,  Stephen Anderson ,  Mark Maloney ,  Shu Yu ,  Ekaterina Albert ,  Emily Rigsbee

IPC分类号： C07D233/88

摘要： The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

公开(公告)号：US10590087B1

公开(公告)日：2020-03-17

申请号：US16537394

申请日：2019-08-09

申请人： Pfizer Inc.

发明人： Elaine Greer ,  Stephen Anderson ,  Mark Maloney ,  Shu Yu ,  Ekaterina Albert ,  Emily Rigsbee

IPC分类号： C07D233/88 ,  A61K31/40

摘要： The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

公开(公告)号：US12116347B2

公开(公告)日：2024-10-15

申请号：US18414019

申请日：2024-01-16

申请人： PFIZER INC.

发明人： Elaine Greer ,  Stephen Anderson ,  Mark Maloney ,  Shu Yu ,  Ekaterina Albert ,  Emily Rigsbee

IPC分类号： C07D233/88 ,  A61K31/40

CPC分类号： C07D233/88 ,  A61K31/40 ,  C07B2200/13

摘要： The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

公开(公告)号：US11884635B2

公开(公告)日：2024-01-30

申请号：US18361545

申请日：2023-07-28

申请人： Pfizer Inc.

发明人： Elaine Greer ,  Stephen Anderson ,  Mark Maloney ,  Shu Yu ,  Ekaterina Albert ,  Emily Rigsbee

IPC分类号： C07D233/88 ,  A61K31/40

CPC分类号： C07D233/88 ,  A61K31/40 ,  C07B2200/13

摘要： The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.