- 专利标题: Enteric coated multiparticulate compositions with a proteinaceous subcoat
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申请号: US17528689申请日: 2021-11-17
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公开(公告)号: US11826475B2公开(公告)日: 2023-11-28
- 发明人: Syed M. Shah , Fred Hassan
- 申请人: Société des Produits Nestlé S.A.
- 申请人地址: CH Vevey
- 专利权人: Société des Produits Nestlé S.A.
- 当前专利权人: Société des Produits Nestlé S.A.
- 当前专利权人地址: CH Vevey
- 代理机构: GrayRobinson, P.A.
- 代理商 Christopher M. Ramsey
- 主分类号: A61K9/50
- IPC分类号: A61K9/50 ; A61K9/00 ; A61K9/20 ; A61K9/48 ; A61K31/045 ; A61K36/23 ; A61K36/534 ; A61K36/82 ; A61P1/00 ; A61P1/04 ; A61P1/12 ; A61P1/14 ; A61K9/16 ; A61K47/26 ; A61K47/38
摘要:
A method of treating a gastrointestinal disorder includes administering to a patient an effective amount of a multiparticulate dosage form including a plurality of individual spheroidal enteric coated cores having a diameter of 0.1 mm to 3 mm. The individual spheroidal enteric coated cores have (a) a core including menthol, (b) a proteinaceous subcoating over the core, and (c) an enteric coating over the proteinaceous subcoating. The multiparticulate dosage form is configured to release most of the menthol in the area of the GI tract where the inflammation is occurring.
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