- 专利标题: Antibodies to alpha-synuclein and uses thereof
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申请号: US17152051申请日: 2021-01-19
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公开(公告)号: US11827695B2公开(公告)日: 2023-11-28
- 发明人: Michael K. Ahlijanian , Jere Ernest Meredith, Jr. , Nino Devidze , John David Graef , Edward L. Halk
- 申请人: BRISTOL-MYERS SQUIBB COMPANY
- 申请人地址: US NJ Princeton
- 专利权人: Bristol-Myers Squibb Company
- 当前专利权人: Bristol-Myers Squibb Company
- 当前专利权人地址: US NJ Princeton
- 代理机构: Nelson Mullins Riley & Scarborough LLP
- 代理商 Jane E. Remillard, Esq.; Jill Gorny Sloper, Esq.
- 主分类号: C07K16/18
- IPC分类号: C07K16/18 ; A61K39/395 ; A61P25/16 ; A61P25/28
摘要:
Disclosed herein are anti-α-synuclein antibodies which preferentially bind to oligomeric α-synuclein over monomeric α-synuclein, therapeutic compositions comprising the antibodies, and methods of using the antibodies to treat synucleinopathies.
公开/授权文献
- US20210221878A1 ANTIBODIES TO ALPHA-SYNUCLEIN AND USES THEREOF 公开/授权日:2021-07-22
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