The present disclosure provides techniques for optimizing power consumption of Massive-Internet of Things (IoT) devices comprising a plurality of IoT devices. According to some examples, a power optimizer system may obtain one or more operational parameters of a plurality of IoT devices. The power optimizer system may estimate a Power Cost Function (PCF) based on one or more operational parameters to determine power consumption of each IoT device. The power optimizer system may determine a variation in the PCF of one or more IoT devices out of the plurality of IoT devices due to variations in uplink and downlink operations of each IoT device. The power optimizer system may identify one or more optimal operational parameters and then, configure the one or more IoT devices of the plurality of IoT devices with the one or more optimal operational parameters.