Barcode readers with transflective mirrors are disclosed herein. An example barcode reader includes a housing and a window positioned within the housing, an imaging sensor and second imaging sensor positioned within the housing, and a transflective mirror positioned within the housing and in a path of a field-of-view of the imaging sensor. The field-of-view of the imaging sensor passes through the transflective mirror and out the window with the transflective mirror in a transmissive state and the field-of-view of the second imaging sensor is reflected off of the transflective mirror and out the window with the transflective mirror in a reflective state.