Vehicle chassis with interchangeable performance packages and related methods. are disclosed herein. An example vehicle chassis disclosed herein includes a frame including a first chassis portion including a cavity, a battery platform coupled to first chassis portion, and a first subframe couplable within the cavity, the first subframe including a first motor and a first suspension assembly, and a second subframe couplable within the cavity, the second subframe including a second motor and a second suspension assembly, the second motor having a greater power than the first motor, the second suspension assembly having a greater stiffness than the first suspension assembly.