An optical compensation system based on artificial intelligence according to embodiments of the present disclosure may include a measuring device configured to measure optical characteristics of a display panel, and output measurement result data of the optical characteristics, and an artificial intelligence-based optical compensation controller configured to predict and generate optical compensation result data corresponding to the measurement result data of the optical characteristics based on an artificial intelligence neural network using previous optical compensation result data for at least one other display panel, and store the predicted and generated optical compensation result data in a memory corresponding to the display panel.