A catalyst article is provided including a substrate including a plurality of passageways, and further including a first and a second oxidation region including a first and a second subset of said plurality of passageways. A first catalyst composition is coating at least a portion of each passageway of the first oxidation region and positioned as a sole PGM-containing catalyst layer, or a zoned portion thereof, or as a top PGM-containing catalyst layer, or a zoned portion thereof, in the first oxidation region. A second catalyst composition is coating at least a portion of each passageway of the second oxidation region and positioned as a sole PGM-containing catalyst layer, or a zoned portion thereof, or as a top PGM-containing catalyst layer, or a zoned portion thereof, in the second oxidation region. The Pt:Pd weight ratio is greater in the first catalyst composition than in the second catalyst composition.